Viagra for pulmonary htn

Author: cosmicMichaelextra | 2024-08-18 06:02:54

Sildenafil (oral route) - Mayo Clinic

Tab: Edema associated w/ heart failure including pulmonary edema, renal &, hepatic disorders &, may be effective in patients unresponsive to thiazide diuretics. HTN as monotherapy or w/ other antihypertensives. Management of oliguria due to renal failure or insufficiency. Soln for inj: Edema associated w/ CHF, cirrhosis of the liver &, renal disease including the nephrotic syndrome. Adjunct in the treatment of acute pulmonary edema &, cerebral edema where intense &, rapid onset of diuresis is desired. Adjunct to antihypertensive agents in the treatment of hypertensive crisis (especially when associated w/ acute pulmonary edema or renal failure).Place of OriginPhilippinesProduct UsageTab Adult 20-80 mg single daily dose preferably in the morning, may be titrated & given in divided doses every 6-8 hr. Edema Initially 40 mg in the morning. Maintenance: 20-40 mg daily, may be increased to ≥80 mg daily in resistance edema. HTN 40-80 mg daily as monotherapy or w/ other antihypertensives. Childn Initially 2 mg/kg/dose, may be increased by 1-2 mg/kg every 6-8 hr. Max: 6 mg/kg w/ interval of at least 2 hr between doses. Edema Initially 1-3 mg/kg daily. Max: 40 mg daily. HTN Adult dose. Chronic renal impairment Oliguria Initially 250 mg, may be increased in steps of 250 mg every 4-6 hr if necessary. Max: 1.5 g in 24 hr. Soln for inj Inj or infused slowly over 1-2 min at a rate not exceeding 4 mg/min. Adult Edema Initially 20-40 mg IM/iv as single dose, may be administered in the same manner 2 hr later or may be increased by 20 mg & given no sooner than 2 hr after previous dose. Acute pulmonary edema Initially 40 mg by slow IV, may be increased to 80 mg by slow IV. Cerebral edema 20-40 mg tid by slow IV. Hypertensive crisis 40-80 mg IV (w/

Revised Definition of Pulmonary Hypertension and Approach to

• Five groups of conditions have been classified as leading to PH: (1) pulmonary arterial hypertension (PAH); (2) a reaction to left-sided heart disease; (3) illnesses that emerge from either lung diseases or hypoxia; (4) chronic thromboembolism and (5) a grouping for unclear, unknown, multifactorial mechanisms [].Because of the severity of PH and its complications, it
• If you take sildenafil for pulmonary arterial hypertension, do not take Viagra or other PDE5 inhibitors, including tadalafil (Cialis ) or vardenafil (Levitra ). Viagra also contains sildenafil. If you take too much sildenafil or take it together with
• Additional studies of patients with heart failure and pulmonary hypertension demonstrated that sildenafil treatment was associated with improved ventilator efficiency, as determined by Ve/VCO 2 slope by cardiopulmonary stress testing, and correlated with drops in pulmonary vascular resistance and improvement in RV ejection fraction.64

Sildenafil (Viagra - Cigna

Select a medication above to begin. sildenafil Adult Dosing . Dosage forms: TAB: 20 mg; SUSP: 10 mg per mL; INJ: various pulmonary arterial HTN [20 mg PO tid] Max: 240 mg/day PO; Alt: 10 mg IV q8h; Info: space doses 4-6h apart renal dosing [see below] renal impairment: no adjustment HD/PD: not defined hepatic dosing [see below] Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined Peds Dosing . Dosage forms: TAB: 20 mg; SUSP: 10 mg per mL pulmonary arterial HTN [ Dose: 0.5-1 mg/kg/dose PO tid; Info: space doses 4-6h apart [1-17 yo, Dose: 10 mg PO tid; Info: space doses 4-6h apart [1-17 yo, 20-45 kg] Dose: 20 mg PO tid; Info: space doses 4-6h apart [1-17 yo, >45 kg] Dose: 20 mg PO tid; Max: 120 mg/day; Info: space doses 4-6h apart persistent pulmonary HTN of newborn, refractory (off-label) [ Dose: 0.5-1 mg/kg/dose PO tid; Info: for adjunct tx; space doses 4-6h apart; delay tx start in extremely premature infants until retinal vascularization established renal dosing [see below] renal impairment: no adjustment HD/PD: not defined hepatic dosing [see below] Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined Contraindications / Cautions . hypersensitivity to drug or ingredient pulmonary veno-occlusive dz (pulmonary HTN use) caution: pts >50 yo caution: smokers caution: CrCl caution: hepatic impairment (erectile dysfxn use) caution: HTN caution: BP caution: hypovolemia caution: aortic stenosis caution: IHSS caution: autonomic dysfxn caution: NYHA Class II-IV CHF w/in 6mo (erectile

Medications for Pulmonary Arterial Hypertension - Drugs.com

Viagra for pulmonary htn	cosmicMichaelextra	Pulmonary hypertension - Wikipedia
Viagra (Sildenafil): Uses, Benefits and Side Effects - hims	(4.6 / 1748 reviews)	Pulmonary hypertension (PH) is a serious health condition that results when the arteries carrying blood from the right side of the heart to the lungs are constricted, disrupting the flow of blood.

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Pulmonary arterial HTN functional class II & III in adult patients. Primary pulmonary & pulmonary HTN associated w/ connective tissue disease. Adult ≥18 yr 20 mg tds taken approx 6-8 hr apart. Patient receiving CYP3A4 inhibitors eg, erythromycin or saquinavir 20 mg bd. Patient receiving more potent CYP3A4 inhibitors eg, clarithromycin, telithromycin, nefazodone 20 mg once daily. Renal & hepatic impairment 20 mg bd only if therapy is not well tolerated. May be taken with or without food. Hypersensitivity. Recent history of stroke or MI, severe hypotension (BP Discontinue use if any sudden visual defects occur. Not recommended in other forms of pulmonary arterial HTN; known hereditary degenerative retinal disorders eg, retinitis pigmentosa. Not to be used in patients w/ pulmonary HTN secondary to sickle cell anaemia. Anatomical penis deformation (eg, angulation, cavernosal fibrosis or Peyronie's disease) or conditions predisposing to priapism eg, sickle cell anaemia, multiple myeloma or leukemia. Serious CV events eg, MI, unstable angina, sudden cardiac death, ventricular arrhythmia, cerebrovascular haemorrhage, transient ischaemic attack, HTN, hypotension. Pulmonary arterial HTN functional class I & IV; fluid depletion, severe left ventricular outflow obstruction or autonomic dysfunction; NAION; bleeding disorders or active peptic ulceration; pulmonary HTN associated w/ pulmonary veno-occlusive disease; hearing impairment. Avoid abrupt discontinuation. Not to be taken by patients w/ galactose intolerance, total lactase deficiency or glucose-galactose malabsorption. Not recommended in concomitant use w/ other PDE5 inhibitors. Concomitant use w/ α-blockers, vit K antagonist, bosentan. May affect ability to drive & use machines. Not recommended in women of childbearing potential. Not to be used during pregnancy. Lactation. Not recommended in childn Headache; flushing; diarrhoea, dyspepsia; pain in extremity. Cellulitis, flu, bronchitis, sinusitis, rhinitis, gastroenteritis; anaemia; fluid retention; insomnia, anxiety; migraine, tremor, paresthesia, burning sensation, hypoaesthesia; retinal haemorrhage, visual impairment, blurred vision, photophobia, chromatopsia, cyanopsia, eye irritation, ocular hyperaemia; vertigo; epistaxis, cough, nasal congestion; gastritis, GERD, haemorrhoids, abdominal distension, dry mouth; alopecia, erythema, night sweats; myalgia, back pain; pyrexia. Reduced clearance w/ CYP3A4 inhibitors. Increased clearance w/ CYP3A4 inducers. Reduced clearance &/or increased oral bioavailability w/ CYP3A4 substrates & β-blockers. Decreased exposure w/ bosentan. Increased Cmax & plasma

Pulmonary hypertension (PAH), right ventricular dysfunction, dysrhythmia, and ischemic coronary disease are known severe consequences of COPD progression [48,49]. Patients with COPD are particularly vulnerable to cardiac disease, with a higher incidence and prevalence (age- and sex-adjusted) compared with patients without COPD [ 50 ]. Exaggerated hypoxic pulmonary vasoconstriction is a key factor in the development of high altitude pulmonary edema (HAPE). Due to its effectiveness as a pulmonary vasodilator, sildenafil has been proposed as a prophylactic agent against HAPE. By conducting a parallel-group double blind, randomized